SIDE EFFECTS. In clinical trials, generally mild and transient burning and stinging followed application with ELIMITE™ (permethrin) 5% Cream in 10% of patients and was associated with the severity of infestation. Well, you might be using a permethrin based solution for this. But, if you are not getting rid of the problem or if the itching sensation seems to continue, you need think for another solution. Find out what all you can do. The most common side effect of permethrin cream for scabies is intense itching that may worsen once treatment begins. Even if all the scabies mites and their eggs have died, itching, stinging, or burning may continue for up to two weeks after treatment with permethrin cream. If you are sleeping in the same bed with your spouse and have not become reinfested, and you have not retreated yourself for at least 30 days, then it is unlikely that your spouse has scabies. After using permethrin, sanitize all the clothing, underwear, pajamas, hats, sheets, pillowcases, and towels you have used recently. These items should be washed in very hot water or dry-cleaned. You should also wash combs, brushes, hairs clips and other personal care items in hot water. What do I need to tell my doctor BEFORE I take Permethrin Cream? If you have an allergy to permethrin , chrysanthemums, or any other part of permethrin cream. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. After being treated you may still itch for 2 to 4 more weeks until the allergic reaction has completely resolved. Search Sign Up Login About. Doctor How long after using permethrin do scabies stop itching?. I have talked to many doctors already, and done some research myself. Most of them say that the mites will be gone within a day, but you may itch up to 2-3 weeks because the skin is still irritated. Personalized insights from top U.S. Doctors: Learn about how long itching can persist after using premethrin cream for scabies mites from Dr. Harris. Personalized insights from top U.S. Doctors: Learn about how long itching can persist after using premethrin cream for scabies mites from Dr. Harris.